Trasylol 10 000 KIU/mL Injection
PDF Leaflet Revision Date: 14 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis to reduce blood loss in high-risk adult patients undergoing isolated cardiopulmonary bypass graft surgery.
Dosage (summary)
Test dose of 1 mL (10,000 KIU) prior to therapeutic dose; loading dose of 1-2 million KIU followed by continuous infusion of 250,000-500,000 KIU/hour.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Use with caution in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Thrombolytic agents
- Aminoglycosides
Contraindications
- Hypersensitivity to aprotinin
- Pancreatitis
- Positive aprotinin-specific IgG test
Common side effects
- Allergic reactions
- Myocardial infarction
- Acute renal failure
Counselling Points
- Test dose required before full dose
- Monitor for allergic reactions
- Ensure emergency treatment available
Serious warnings
- Increased risk of anaphylaxis upon re-exposure
- Not for use in combined cardiovascular surgeries
Important Disclaimer
The Trasylol 10 000 KIU/mL Injection professional information leaflet below is the property of Equity Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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