Zoczen Capsules
PDF Leaflet Revision Date: 01 February 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prevention of uncomplicated lower urinary tract infections.
Dosage (summary)
50 mg to 100 mg four times daily with meals; 50 mg to 100 mg daily for prevention.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safe in pregnancy except at term; contraindicated in breastfeeding if infant has G6PD deficiency.
Key Drug Interactions
- Probenecid
- Sulfinpyrazone
- Magnesium trisilicate
- Quinolones
Contraindications
- G6PD deficiency
- Anuria
- Oliguria
- Renal impairment (eGFR < 45 mL/min)
- Pregnant women at term
Common side effects
- Nausea
- Dizziness
- Peripheral neuropathy
- Pulmonary reactions
Counselling Points
- Take with food to minimize gastric upset
- Report signs of peripheral neuropathy
- Urine may turn brown
Serious warnings
- Prolonged use not recommended
- Risk of pulmonary toxicity
- Monitor for hemolytic anemia
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