Zolpidem 12,5 mg XR tablets
PDF Leaflet Revision Date: 20 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Short-term treatment of insomnia in adults under 65.
Dosage (summary)
12.5 mg once daily before bedtime; max duration 4 weeks.
Onset of Action / Duration
Onset: Rapid, Duration: Up to 8 hours
Special Populations
- Hepatic impairment
- Elderly patients
- Renal impairment
Pregnancy & Breastfeeding
Avoid in pregnancy and breastfeeding; potential neonatal effects.
Key Drug Interactions
- Alcohol
- CNS depressants
- Opioids
- CYP450 inhibitors
Contraindications
- Hypersensitivity to zolpidem
- Children under 18
- Severe hepatic impairment
- Sleep apnoea syndrome
- Myasthenia gravis
Common side effects
- Somnolence
- Dizziness
- Headache
- Anxiety
Counselling Points
- Take immediately before bed.
- Avoid alcohol and CNS depressants.
- Do not drive if drowsy.
- Monitor for signs of dependence.
Serious warnings
- Risk of dependence
- Amnesia
- Respiratory depression
- Suicidality
Important Disclaimer
The Zolpidem 12,5 mg XR tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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