Bevacizumab 100 & 400 Equity 100mg & 400 mg Concentrate for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including metastatic colorectal, breast, lung, and renal cell cancers.
Dosage (summary)
5-15 mg/kg IV every 2-3 weeks depending on cancer type.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; discontinue breastfeeding during treatment.
Key Drug Interactions
- Sunitinib
- Chemotherapy agents
Contraindications
- Hypersensitivity
- Untreated CNS metastases
- Pregnancy
- Lactation
Common side effects
- Hypertension
- Fatigue
- Diarrhoea
- Abdominal pain
Counselling Points
- Monitor blood pressure
- Report signs of bleeding
- Avoid pregnancy during treatment
Serious warnings
- Gastrointestinal perforations
- Arterial thromboembolism
- Wound healing complications
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