Bupropion XR 150 Adco 150 mg. Extended-release tablets.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression.
Dosage (summary)
Initial: 150 mg once daily; may increase to 300 mg once daily.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; potential risk of congenital malformations. Avoid breastfeeding.
Key Drug Interactions
- MAOIs
- CYP2D6 substrates
- Alcohol
Contraindications
- Under 18 years
- Seizure disorder
- Hypersensitivity
- Bulimia or anorexia
- Severe hepatic cirrhosis
Common side effects
- Insomnia
- Dry mouth
- Headache
- Increased blood pressure
Counselling Points
- Swallow tablets whole.
- Monitor for worsening depression or suicidal thoughts.
- Avoid alcohol.
Serious warnings
- Risk of seizures
- Suicidal ideation
- Caution in cardiovascular disease
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