Tegretol 200 mg and 400 mg Tablets, Divitabs, Suspension

Tegretol 200 mg and 400 mg Tablets, Divitabs, Suspension

S3
PDF Leaflet Revision Date: 07 October 2024


Clinical Summary

Quick overview from the medicine insert

Indication

Epilepsy, bipolar disorder, trigeminal neuralgia.

Dosage (summary)

Adults: 100-200 mg once/twice daily, increase to 400 mg 2-3 times daily. Max 1600 mg/day.

Onset of Action / Duration

Onset: 30 mins, Duration: 12-24 hours

Special Populations

  • Elderly
  • Children
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Risk of fetal harm; avoid breastfeeding.

Key Drug Interactions

  • CYP3A4 inducers/inhibitors
  • Hormonal contraceptives
  • MAOIs

Contraindications

  • Hypersensitivity
  • AV block
  • Bone-marrow depression
  • Porphyria
  • SJS/TEN history

Common side effects

  • Dizziness
  • Drowsiness
  • Nausea
  • Allergic skin reactions

Counselling Points

  • Monitor for skin reactions
  • Avoid abrupt withdrawal
  • Use effective contraception

Serious warnings

  • Serious skin reactions
  • Hematological effects
  • Suicidal ideation

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Tegretol 200 mg and 400 mg Tablets, Divitabs, Suspension
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