Auroxime 125 mg/ 250 mg/ 500 mg Tablet
PDF Leaflet Revision Date: 08 January 2026
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible strains.
Dosage (summary)
Adults: 250 mg twice daily for sinusitis/bronchitis; 125 mg twice daily for cystitis; 500 mg twice daily for Lyme disease.
Special Populations
- Renal impairment
- Children under 3 months
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established; excreted in breast milk.
Key Drug Interactions
- Probenecid increases serum concentration
- Avoid furosemide due to nephrotoxicity
- May decrease efficacy of oral contraceptives
Contraindications
- Hypersensitivity to cephalosporins
- Hypersensitivity to penicillin
- Pregnancy and breastfeeding
Common side effects
- Nausea
- Diarrhoea
- Headache
- Dizziness
- Candida overgrowth
Counselling Points
- Take half an hour after food
- Report severe allergic reactions
- Monitor for signs of Clostridium difficile infection
Serious warnings
- Serious hypersensitivity reactions
- Risk of pseudomembranous colitis
- Jarisch-Herxheimer reaction in Lyme disease
Important Disclaimer
The Auroxime 125 mg/ 250 mg/ 500 mg Tablet professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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