Klacid P125 & P250 125mg / 5ml. 250mg / 5ml Granules
PDF Leaflet Revision Date: 7 July 2006
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections due to susceptible organisms.
Dosage (summary)
Children: 7.5 mg/kg twice daily; max 500 mg twice daily.
Onset of Action / Duration
Onset: 2.5 hours, Duration: 3.2 hours
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety not established; excreted in breast milk.
Key Drug Interactions
- Warfarin
- Colchicine
- CYP3A substrates
Contraindications
- Hypersensitivity to macrolides
- Concomitant use with terfenadine
Common side effects
- Diarrhoea
- Vomiting
- Abdominal pain
- Rash
Counselling Points
- Take with or without food
- Monitor for signs of toxicity
- Avoid in severe renal impairment
Serious warnings
- Pseudomembranous colitis
- Colchicine toxicity
- QT prolongation
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