Drymred 500 500 mg (Lyophilized powder for IV infusion
PDF Leaflet Revision Date: 25 March 2019
Clinical Summary
Quick overview from the medicine insert
Indication
Complicated skin and skin structure infections and Staphylococcus aureus bloodstream infections.
Dosage (summary)
4 mg/kg IV daily for cSSSI; 6 mg/kg IV daily for bloodstream infections.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
- Obesity
Pregnancy & Breastfeeding
Not established; avoid in pregnancy; caution in breastfeeding.
Key Drug Interactions
- Warfarin
- Tobramycin
- HMG-CoA reductase inhibitors
Contraindications
- Hypersensitivity to daptomycin
Common side effects
- Candida infections
- Anemia
- Diarrhea
- Nausea
- Headache
Counselling Points
- Monitor for muscle pain and CPK levels
- Avoid driving if dizzy
- Report any allergic reactions
Serious warnings
- Not effective for pneumonia
- Risk of myopathy
- Clostridium difficile-associated diarrhea
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