Dienogest Adco 2mg Tablet

Dienogest Adco 2mg Tablet

S3
PDF Leaflet Revision Date: 28 February 2022

API: Dienogest | Company: Adcock Ingram

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of endometriosis.

Dosage (summary)

1 tablet daily, starting on day 1 of menstrual cycle, without breaks.

Special Populations

  • Adolescents
  • Women with hypertension
  • Diabetic women

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation.

Key Drug Interactions

  • CYP3A4 inducers (e.g., rifampicin)
  • CYP3A4 inhibitors (e.g., ketoconazole)

Contraindications

  • Hypersensitivity to dienogest
  • Known or suspected pregnancy
  • Lactation
  • History of venous thromboembolic disorder
  • Arterial and cardiovascular diseases
  • Severe hepatic disease
  • Sex hormone-dependent malignancies
  • Undiagnosed vaginal bleeding

Common side effects

  • Headache
  • Breast discomfort
  • Depressed mood
  • Acne

Counselling Points

  • Take at the same time daily
  • Use non-hormonal contraception if needed
  • Monitor for signs of thrombotic events

Serious warnings

  • Risk of thromboembolism
  • Changes in bleeding pattern
  • Potential decrease in bone mineral density

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