Ketamine Fresenius 10 mg. 50 mg or 100 mg Solution for injection or infusion
PDF Leaflet Revision Date: 25 April 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Induction and maintenance of general anaesthesia.
Dosage (summary)
IV: 1-2 mg/kg; IM: 5-10 mg/kg.
Onset of Action / Duration
Onset: 30 secs (IV), 3-4 mins (IM); Duration: 5-25 mins.
Special Populations
- Hepatic impairment
- Renal impairment
- Hypertension
- Cerebral trauma
- Psychiatric disorders
Pregnancy & Breastfeeding
Safety not established; crosses placenta, may cause respiratory depression in neonates.
Key Drug Interactions
- Incompatible with barbiturates and diazepam
- Increases effects of CNS depressants
- May potentiate neuromuscular blockers
Contraindications
- Hypersensitivity to ketamine
- Severe hypertension
- Eclampsia or pre-eclampsia
- Cerebral trauma
- Increased intra-ocular pressure
Common side effects
- Hallucinations
- Increased blood pressure
- Nausea
- Respiratory depression
- Dysrhythmias
Counselling Points
- Avoid driving for 24 hours post-administration.
- Do not consume alcohol for 24 hours.
- Monitor for emergence reactions.
Serious warnings
- Respiratory depression with overdose
- Emergence reactions
- Caution in cardiac disease
Important Disclaimer
The Ketamine Fresenius 10 mg. 50 mg or 100 mg Solution for injection or infusion professional information leaflet below is the property of Fresenius Kabi Manufacturing Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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