Propofol 0.5 % (5 Mg/Ml) B. Braun 5 mg Emulsion for injection or infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
Induction of general anaesthesia and sedation for procedures.
Dosage (summary)
Adults: 1.5-2.5 mg/kg for induction; Elderly: reduced dose required.
Onset of Action / Duration
Onset: 30-40 secs, Duration: 4-6 mins
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; avoid breastfeeding for 24 hours post-administration.
Key Drug Interactions
- CNS depressants
- Opioids
- Benzodiazepines
Contraindications
- Hypersensitivity to propofol
- Children < 3 years
- Sedation in intensive care
Common side effects
- Hypotension
- Apnoea
- Bradycardia
Counselling Points
- Avoid alcohol for 24 hours
- Do not drive or operate machinery post-use
- Monitor for respiratory depression
Serious warnings
- Respiratory depression
- Risk of anaphylaxis
- Not for maintenance of anaesthesia
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