Norvir 100 mg TABLET, Powder for Oral Suspension
Clinical Summary
Quick overview from the medicine insert
Indication
Used as a pharmacokinetic enhancer of certain antiretroviral protease inhibitors.
Dosage (summary)
Adults: Consult specific protease inhibitor guidelines. Pediatric: 400 mg/mu00b2 twice daily, max 600 mg.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; safety not established.
Key Drug Interactions
- CYP3A4 inhibitors
- Sedative/hypnotics
- Antidysrhythmics
Contraindications
- Hypersensitivity to ritonavir
- Severe liver disease
- Rifampicin regimens
Common side effects
- Nausea
- Diarrhea
- Vomiting
- Abdominal pain
- Taste perversion
Counselling Points
- Take with food
- Monitor for liver function
- Avoid St. John's Wort
Serious warnings
- Serious hepatic reactions
- Pancreatitis risk
- Diabetes mellitus
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