Adco Tenofovir 300 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretroviral agents.
Dosage (summary)
The recommended dosage for adults and adolescents is one tablet (300 mg) taken orally once daily.
Onset of Action / Duration
Viral load reduction may be observed within 2 to 4 weeks of initiating therapy.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Tenofovir Disoproxil is classified as Category B3. It is not known if it is excreted in human milk; caution should be exercised when administered to nursing mothers.
Key Drug Interactions
- Didanosine: Increased risk of didanosine toxicity.
- Adefovir: Increased risk of nephrotoxicity.
- Rifampicin: May decrease tenofovir levels.
Contraindications
- Hypersensitivity to tenofovir disoproxil or any component of the formulation.
- Severe renal impairment (CrCl < 50 mL/min).
Common side effects
- Nausea
- Diarrhea
- Headache
- Fatigue
- Renal impairment
Counselling Points
- Take the medication exactly as prescribed.
- Ensure adequate hydration during treatment.
- Regular monitoring of renal function is recommended.
- Inform healthcare provider of any other medications being taken.
Serious warnings
- Risk of lactic acidosis and severe hepatomegaly with steatosis.
- Risk of acute exacerbation of hepatitis B in patients co-infected with HBV.
- Monitor for signs of renal toxicity.
Important Disclaimer
The Adco Tenofovir 300 mg Tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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