Blitzima 100 mg & 500 mg Solution

    Blitzima 100 mg & 500 mg Solution

    S4
    PDF Leaflet Revision Date: 17 January 2025

    API: Rituximab | Company: Adcock Ingram

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of various B-cell malignancies and autoimmune diseases.

    Dosage (summary)

    375 mg/mu00b2 IV weekly for 4 weeks for NHL; 1000 mg IV for RA, followed by 1000 mg 2 weeks later.

    Special Populations

    • Elderly
    • Paediatric population

    Pregnancy & Breastfeeding

    Not recommended during pregnancy; avoid breastfeeding during and for 12 months after treatment.

    Key Drug Interactions

    • Methotrexate
    • Fludarabine
    • Cyclophosphamide

    Contraindications

    • Hypersensitivity to rituximab
    • Active severe infections
    • Severe heart failure

    Common side effects

    • Infusion-related reactions
    • Infections
    • Neutropenia

    Counselling Points

    • Monitor for infusion reactions
    • Use effective contraception during treatment
    • Report any signs of infection immediately

    Serious warnings

    • Progressive multifocal leukoencephalopathy (PML)
    • Tumour lysis syndrome
    • Hepatitis B reactivation
    Important Disclaimer

    The Blitzima 100 mg & 500 mg Solution professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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