Caphet 60 Mg/1.5 Ml Iv 60 mg Concentrate for solution for infusion
PDF Leaflet Revision Date: 27 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hormone refractory metastatic prostate cancer.
Dosage (summary)
25 mg/mu00b2 IV infusion every 3 weeks with daily prednisone 10 mg.
Special Populations
- Elderly u2265 65 years
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- Strong CYP3A inhibitors
- Strong CYP3A inducers
Contraindications
- Hypersensitivity to cabazitaxel
- Neutrophil counts u2264 1,500/mmu00b3
- Hepatic impairment
- Concomitant yellow fever vaccination
Common side effects
- Neutropenia
- Diarrhoea
- Fatigue
- Hypersensitivity reactions
Counselling Points
- Premedicate to reduce hypersensitivity risk
- Monitor for neutropenia
- Avoid live vaccines
Serious warnings
- Severe hypersensitivity reactions
- Bone marrow suppression
- Risk of cardiac dysrhythmias
Important Disclaimer
The Caphet 60 Mg/1.5 Ml Iv 60 mg Concentrate for solution for infusion professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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