Dunarid 400 & 800 400 mg, 800 mg Tablet

    Dunarid 400 & 800 400 mg, 800 mg Tablet

    S4
    PDF Leaflet Revision Date: 16 May 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of HIV infection in antiretroviral treatment experienced adult patients.

    Dosage (summary)

    800 mg darunavir with 100 mg ritonavir once daily with food.

    Special Populations

    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Safety not established; avoid breastfeeding.

    Key Drug Interactions

    • CYP3A inducers
    • Rifampicin
    • St. John's Wort

    Contraindications

    • Hypersensitivity to darunavir
    • Severe hepatic impairment

    Common side effects

    • Rash
    • Nausea
    • Diarrhea
    • Headache

    Counselling Points

    • Take with food
    • Monitor for skin reactions
    • Avoid alcohol

    Serious warnings

    • Severe skin reactions
    • Hepatotoxicity
    • Increased bleeding in hemophilia
    Important Disclaimer

    The Dunarid 400 & 800 400 mg, 800 mg Tablet professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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