Crestor 5 5mg. 10mg. 20mg. 40mg Tablet
PDF Leaflet Revision Date: 26 October 2012
Clinical Summary
Quick overview from the medicine insert
Indication
To reduce risk of cardiovascular events and manage hypercholesterolaemia.
Dosage (summary)
5-40 mg orally once daily; start at 5 mg for most patients.
Onset of Action / Duration
Onset: 1 week, Duration: 4 weeks for maximum response.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
- Asian ancestry
Pregnancy & Breastfeeding
Safety not established; use contraceptive measures.
Key Drug Interactions
- Warfarin
- Ciclosporin
- Gemfibrozil
- Protease inhibitors
- Antacids
Contraindications
- Hypersensitivity
- Active liver disease
- Myopathy
- Concomitant use with ciclosporin
Common side effects
- Headache
- Dizziness
- Constipation
- Nausea
- Myalgia
Counselling Points
- Adhere to cholesterol-lowering diet.
- Monitor for muscle pain or weakness.
- Report any signs of liver issues.
Serious warnings
- Risk of myopathy and rhabdomyolysis
- Increased liver transaminases
- Caution in alcohol use and liver disease
Important Disclaimer
The Crestor 5 5mg. 10mg. 20mg. 40mg Tablet professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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