Fresenius Propoven 1 % 20 ml, 50 ml, 100 ml Emulsion for injection or Infusion
PDF Leaflet Revision Date: 10 June 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Short-acting intravenous general anaesthetic.
Dosage (summary)
Induction: 1.5-2.5 mg/kg; Maintenance: 4-12 mg/kg/h.
Onset of Action / Duration
Onset: 30-40 secs, Duration: 4-6 mins.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Cardiac insufficiency
Pregnancy & Breastfeeding
Not established in pregnancy; excreted in breast milk, discard for 24 hours post-administration.
Key Drug Interactions
- Benzodiazepines may prolong effects.
- Concomitant CNS depressants increase sedation.
- Rifampicin may cause hypotension.
Contraindications
- Hypersensitivity to propofol or excipients.
- Allergy to soya or peanut.
- Children under 3 years.
- Sedation in patients under 16 in ICU.
Common side effects
- Hypotension
- Respiratory depression
- Nausea
- Bradycardia
Counselling Points
- Avoid alcohol for 24 hours post-administration.
- Do not drive or operate machinery for 24 hours.
- Monitor for signs of hypotension and airway obstruction.
Serious warnings
- Propofol infusion syndrome may occur.
- Monitor for respiratory depression.
- Risk of abuse and dependence.
Important Disclaimer
The Fresenius Propoven 1 % 20 ml, 50 ml, 100 ml Emulsion for injection or Infusion professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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