Goutrelefe 0,5 Mg & 1 Mg 0,5 mg & 1 mg FC tablets
PDF Leaflet Revision Date: 11 December 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of acute attacks of gout.
Dosage (summary)
Initial dose: 0.5-1 mg, then 0.5 mg every 2 hours until relief or GI symptoms occur. Max: 6 mg in 3 days.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- P-glycoprotein inhibitors
- Macrolide antibiotics
- Oral anticoagulants
Contraindications
- Hypersensitivity to colchicine
- Severe renal impairment
- Severe hepatic impairment
- Blood dyscrasias
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Diarrhoea
Counselling Points
- Avoid use in pregnancy and breastfeeding
- Report any signs of toxicity
- Use effective contraception in women of childbearing potential
Serious warnings
- Narrow therapeutic window
- Potentially fatal overdose
- Monitor for blood dyscrasias
Important Disclaimer
The Goutrelefe 0,5 Mg & 1 Mg 0,5 mg & 1 mg FC tablets professional information leaflet below is the property of Macleods Pharmaceuticals Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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