Grantryl 1 mg/1 ml & 3 mg/3 ml Injection

    Grantryl 1 mg/1 ml & 3 mg/3 ml Injection

    S4
    PDF Leaflet Revision Date: 28 November 2022

    API: Granisetron | Company: Acino Pharma

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative.

    Dosage (summary)

    Adults: 1-3 mg IV prior to chemotherapy/radiotherapy; max 9 mg/24h. PONV: 1 mg IV prior to anesthesia.

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Contraindicated during pregnancy and lactation.

    Key Drug Interactions

    • Phenobarbital may increase clearance
    • Co-administer with benzodiazepines and neuroleptics

    Contraindications

    • Hypersensitivity
    • Children under 2 years
    • Congenital long QT syndrome

    Common side effects

    • Headache
    • Dizziness
    • Somnolence
    • Abdominal pain
    • Constipation

    Counselling Points

    • Avoid driving if somnolence occurs
    • Report any signs of myocardial ischemia

    Serious warnings

    • May cause dysrhythmias
    • Monitor for myocardial ischemia
    • Max 9 mg/24h
    Important Disclaimer

    The Grantryl 1 mg/1 ml & 3 mg/3 ml Injection professional information leaflet below is the property of Acino Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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