Herceptin 21 mg/mL IV Powder for concentrate for solution for infusion
PDF Leaflet Revision Date: 12 August 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HER2 positive metastatic breast cancer and gastric adenocarcinoma.
Dosage (summary)
Loading dose: 4 mg/kg IV over 90 mins; Maintenance: 2 mg/kg weekly or 8 mg/kg every 3 weeks.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- Capecitabine
- Cisplatin
Contraindications
- Hypersensitivity to trastuzumab
- Severe dyspnoea at rest
- Pregnancy
Common side effects
- Cardiac failure
- Infusion reactions
- Neutropenia
- Diarrhoea
Counselling Points
- Monitor for cardiac function
- Report infusion reactions
- Use effective contraception during treatment
Serious warnings
- Cardiotoxicity
- Severe hypersensitivity reactions
- Pulmonary events
Important Disclaimer
The Herceptin 21 mg/mL IV Powder for concentrate for solution for infusion professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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