Metformin Cr Zydus Range 500 mg/ 750 mg/ 1 000 mg XR tablets.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of type 2 diabetes mellitus in adults.
Dosage (summary)
Starting dose: 500 mg once daily with evening meal; max: 2000 mg once daily.
Special Populations
- Elderly patients
- Renal impairment
- Paediatric population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- Alcohol
- Iodinated contrast agents
- NSAIDs
- Sulphonylureas
Contraindications
- Hypersensitivity to metformin
- Acute metabolic acidosis
- Renal failure
- Hepatic insufficiency
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Loss of appetite
Counselling Points
- Take with food
- Monitor blood glucose regularly
- Report symptoms of lactic acidosis
Serious warnings
- Risk of lactic acidosis
- Monitor renal function
- Discontinue before surgery
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