Methadone Adco 10mg Oral Solution
PDF Leaflet Revision Date: 04 March 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Substitution treatment in opiate dependence.
Dosage (summary)
Initial dose: 20 mg once daily, adjusted to 60-120 mg daily.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or lactation due to risks of neonatal withdrawal and respiratory depression.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- CNS depressants
- MAOIs
Contraindications
- Hypersensitivity
- Children
- Respiratory depression
- Acute alcoholism
- Head injury
- Severe hepatic impairment
Common side effects
- Respiratory depression
- Constipation
- Dizziness
- Nausea
- Fatigue
Counselling Points
- Avoid alcohol and CNS depressants
- Monitor for signs of overdose
- Do not drive until stabilized
- Gradual dose reduction for withdrawal
Serious warnings
- Risk of dependence
- QT prolongation
- Respiratory depression
- CNS depression
Important Disclaimer
The Methadone Adco 10mg Oral Solution professional information leaflet below is the property of Dr Reddy’S Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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