Eptadone 10 10 mg/mL Oral solution
PDF Leaflet Revision Date: 24 June 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Substitution treatment in opiate dependence.
Dosage (summary)
Initial dose: 20 mg once daily, adjusted to 60-120 mg.
Special Populations
- Elderly
- Hepatic impairment
- Hypothyroidism
- Prostatic hypertrophy
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- MAOIs
- CNS depressants
- Gabapentinoids
- Alcohol
- Antiretrovirals
Contraindications
- Hypersensitivity to methadone
- Children
- Respiratory depression
- Acute alcoholism
- Head injury
Common side effects
- Nausea
- Vomiting
- Dizziness
- Sedation
- Constipation
Counselling Points
- Monitor for signs of overdose
- Avoid driving until stabilized
- Gradual dose reduction for withdrawal
- Caution with sedatives
Serious warnings
- Risk of respiratory depression
- Addiction potential
- QT prolongation
- Withdrawal symptoms
Important Disclaimer
The Eptadone 10 10 mg/mL Oral solution professional information leaflet below is the property of Equity Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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