Lometasan 1 Mg/Ml 0,4 mg/mL Oral solution
PDF Leaflet Revision Date: 10 June 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Substitution treatment in opiate dependence.
Dosage (summary)
Initial dose: 20 mg once daily, adjusted to 60-120 mg/day.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or lactation.
Key Drug Interactions
- CNS depressants
- MAO inhibitors
- Antiretroviral medicines
Contraindications
- Hypersensitivity to methadone
- Respiratory depression
- Acute asthma attack
Common side effects
- Nausea
- Vomiting
- Constipation
- Sedation
Counselling Points
- Avoid alcohol and CNS depressants
- Monitor for signs of misuse
- Gradual dose reduction for withdrawal
Serious warnings
- Risk of dependence and overdose
- Respiratory depression
- QT prolongation
Important Disclaimer
The Lometasan 1 Mg/Ml 0,4 mg/mL Oral solution professional information leaflet below is the property of Lebasi Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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