Mirena 52 mg Intrauterine delivery system (IUS)
PDF Leaflet Revision Date: 09 September 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Contraception, idiopathic menorrhagia, endometrial protection during oestrogen therapy.
Dosage (summary)
One unit inserted into the uterine cavity, effective for five years.
Onset of Action / Duration
Onset: Immediate, Duration: 5 years
Special Populations
- Geriatric patients
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; minimal transfer to breast milk.
Key Drug Interactions
- Phenytoin
- Carbamazepine
- Rifampicin
- Azole antifungals
Contraindications
- Hypersensitivity
- Pregnancy
- Pelvic inflammatory disease
- Cervical dysplasia
- Liver disease
Common side effects
- Headache
- Nausea
- Acne
- Bleeding changes
- Ovarian cysts
Counselling Points
- Monitor for signs of expulsion
- Report severe headaches or jaundice
- Regular follow-up exams recommended
Serious warnings
- Risk of perforation
- Increased risk of ectopic pregnancy
- Sepsis risk after insertion
Important Disclaimer
The Mirena 52 mg Intrauterine delivery system (IUS) professional information leaflet below is the property of Bayer and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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