Rubexet Liposomal 20 Mg/10 Ml & 50 Mg/25 Ml 20 mg/10 ml & 50 mg/25 ml Concentrate for solution for infusion
PDF Leaflet Revision Date: 11 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Metastatic breast cancer, advanced ovarian cancer, multiple myeloma, AIDS-related Kaposi's sarcoma.
Dosage (summary)
50 mg/mu00b2 IV every 4 weeks for breast/ovarian cancer; 30 mg/mu00b2 IV on day 4 of bortezomib regimen; 20 mg/mu00b2 IV every 2-3 weeks for AIDS-KS.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding due to potential teratogenic effects.
Key Drug Interactions
- Caution with other cytotoxic agents
- May enhance toxicity of anti-cancer therapies
Contraindications
- Hypersensitivity to doxorubicin or excipients
- Pregnancy
- Breastfeeding
- Ineffective local therapy for AIDS-KS
Common side effects
- Neutropenia
- Nausea
- Fatigue
- Stomatitis
- Palmar-plantar erythrodysaesthesia
Counselling Points
- Avoid pregnancy during and 6 months after treatment
- Monitor for infusion reactions
- Report any signs of cardiac issues
Serious warnings
- Cardiac toxicity monitoring required
- Risk of severe infusion reactions
- Myelosuppression
Important Disclaimer
The Rubexet Liposomal 20 Mg/10 Ml & 50 Mg/25 Ml 20 mg/10 ml & 50 mg/25 ml Concentrate for solution for infusion professional information leaflet below is the property of Accord Healthcare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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