Valeptic Cr 300 mg & 500 mg Prolonged release, FC tablets
PDF Leaflet Revision Date: 23 May 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of generalized and partial epilepsy, and manic episodes in bipolar disorder.
Dosage (summary)
Start at 600 mg/day, increase by 5-10 mg/kg/week; max 2500 mg/day.
Special Populations
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
High teratogenic risk; contraindicated in pregnancy and lactation.
Key Drug Interactions
- Increased sedation with phenobarbital
- Decreased efficacy with carbapenems
- Increased toxicity with zidovudine
Contraindications
- Hypersensitivity to sodium valproate
- Pregnancy
- Active liver disease
Common side effects
- Nausea
- Drowsiness
- Weight gain
Counselling Points
- Monitor for signs of liver dysfunction
- Use effective contraception in women of childbearing potential
- Avoid alcohol during treatment
Serious warnings
- Severe liver damage
- Pancreatitis
- Suicidal ideation
Important Disclaimer
The Valeptic Cr 300 mg & 500 mg Prolonged release, FC tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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