Vcide 20mg / 200mg TABLETS
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of invasive fungal infections.
Dosage (summary)
Loading: 400 mg every 12 hours for 24 hours; Maintenance: 200 mg every 12 hours.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; breastfeeding should be discontinued.
Key Drug Interactions
- CYP3A4 substrates
- Rifampicin
- Carbamazepine
- Phenobarbital
- Ritonavir
Contraindications
- Hypersensitivity to voriconazole
- Prolonged QT syndrome
- Severe hepatic impairment
Common side effects
- Visual impairment
- Rash
- Nausea
- Vomiting
- Liver function test abnormal
Counselling Points
- Take at least 1 hour before or after meals
- Use effective contraception
- Avoid sun exposure
Serious warnings
- QTc prolongation
- Hepatic toxicity
- Serious skin reactions
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