Vorispore 200 mg Powder for solution for infusion
PDF Leaflet Revision Date: June 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of invasive fungal infections.
Dosage (summary)
Loading: 6 mg/kg IV every 12 hours for 24 hours; Maintenance: 3-4 mg/kg IV every 12 hours.
Special Populations
- Elderly: No dose adjustment needed.
- Renal impairment: Caution in moderate to severe cases.
- Hepatic impairment: Monitor liver function.
Pregnancy & Breastfeeding
Not recommended in pregnancy; breastfeeding should be discontinued during treatment.
Key Drug Interactions
- CYP3A4 substrates (e.g., ergot alkaloids, rifampicin) contraindicated.
- Efavirenz: Adjust doses when co-administered.
Contraindications
- Hypersensitivity to voriconazole.
- Severe hepatic impairment.
- Prolonged QT syndrome.
Common side effects
- Visual disturbances.
- Liver function abnormalities.
- Nausea, vomiting.
Counselling Points
- Avoid sun exposure; use sunscreen.
- Monitor for visual changes.
- Report any rash or liver symptoms.
Serious warnings
- QTc prolongation risk.
- Severe hepatic reactions possible.
- Infusion-related reactions.
Important Disclaimer
The Vorispore 200 mg Powder for solution for infusion professional information leaflet below is the property of Astral Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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