Vorzol Iv 200 mg Powder for solution for infusion

Vorzol Iv 200 mg Powder for solution for infusion

S4
PDF Leaflet Revision Date: 19 September 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of invasive fungal infections.

Dosage (summary)

Adults: Loading dose 6 mg/kg every 12 hours for 24 hours, then 3 mg/kg twice daily. Children: Loading dose 6 mg/kg every 12 hours, then 4 mg/kg every 12 hours.

Special Populations

  • Hepatic impairment
  • Children under 2 years

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding.

Key Drug Interactions

  • Ritonavir
  • Carbamazepine
  • Phenobarbital
  • Warfarin
  • Fluconazole

Contraindications

  • Allergy to voriconazole
  • Long QT syndrome
  • Severe hepatic impairment

Common side effects

  • Visual impairment
  • Rash
  • Nausea
  • Fever
  • Elevated liver enzymes

Counselling Points

  • Avoid sun exposure
  • Report visual changes
  • Use effective contraception in women of childbearing potential

Serious warnings

  • Serious skin reactions
  • Liver function monitoring required
  • Adrenal insufficiency risk
Important Disclaimer

The Vorzol Iv 200 mg Powder for solution for infusion professional information leaflet below is the property of Sandoz South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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