Cymbalta 30mg. 60mg Capsule

Cymbalta 30mg. 60mg Capsule

S5
PDF Leaflet Revision Date: 24 January 2022

API: Duloxetine | Company: Eli Lilly

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of depression and Diabetic Peripheral Neuropathic Pain.

Dosage (summary)

60 mg once daily for adults; 30 mg once daily for renal/hepatic impairment.

Onset of Action / Duration

Onset: 2-4 weeks, Duration: Not specified.

Special Populations

  • Renal impairment
  • Hepatic impairment
  • Elderly

Pregnancy & Breastfeeding

Not recommended during pregnancy; safety in breastfeeding not established.

Key Drug Interactions

  • MAOIs
  • CYP1A2 inhibitors
  • CYP2D6 inhibitors
  • Serotonergic medicines

Contraindications

  • Hypersensitivity to duloxetine
  • Severe hepatic impairment
  • Advanced renal impairment
  • Concomitant MAOIs
  • Patients under 18 years

Common side effects

  • Nausea
  • Headache
  • Dry mouth
  • Somnolence
  • Dizziness

Counselling Points

  • Avoid abrupt discontinuation
  • Monitor for suicidal thoughts
  • Caution with alcohol
  • Report any distressing thoughts

Serious warnings

  • Risk of suicide
  • Serotonin syndrome
  • Increased blood pressure
  • Hyponatraemia
Important Disclaimer

The Cymbalta 30mg. 60mg Capsule professional information leaflet below is the property of Eli Lilly and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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