Gactazel 40 Mg 40 mg Powder for solution for injection and infusion
PDF Leaflet Revision Date: 22 October 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of gastro-oesophageal reflux disease and prevention of rebleeding in ulcers.
Dosage (summary)
40 mg IV once daily for erosive reflux; 80 mg bolus for bleeding ulcers.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Caution in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- Clopidogrel
- Warfarin
- Tacrolimus
Contraindications
- Hypersensitivity to esomeprazole
- Concomitant use with nelfinavir and atazanavir
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
Counselling Points
- Monitor for signs of hypomagnesaemia
- Report any severe skin reactions
- Avoid alcohol and NSAIDs
Serious warnings
- Risk of gastrointestinal infections
- Hypomagnesaemia
- Increased risk of fractures
Important Disclaimer
The Gactazel 40 Mg 40 mg Powder for solution for injection and infusion professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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