Linezolid 600 Mg/300 Ml Fresenius 600 mg/300 mL Solution for infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible Gram-positive bacteria.
Dosage (summary)
600 mg IV every 12 hours for adults; 10 mg/kg IV every 8 hours for children.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Serotonergic medicines
- MAO inhibitors
- Pethidine
Contraindications
- Hypersensitivity to linezolid
- MAO inhibitors
- Breastfeeding
Common side effects
- Diarrhoea
- Nausea
- Headache
- Insomnia
Counselling Points
- Avoid tyramine-rich foods
- Monitor for visual changes
- Report signs of serotonin syndrome
Serious warnings
- Serotonin syndrome
- Myelosuppression
- Lactic acidosis
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