Asacol 500mg Suppositories
Clinical Summary
Quick overview from the medicine insert
Indication
Management of ulcerative colitis and Crohn's disease.
Dosage (summary)
The usual dose is 1 to 4 g per day, administered as 500 mg suppositories, divided into two or more doses.
Onset of Action / Duration
Onset of action may take several days to weeks; duration of effect varies based on individual response.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Use during pregnancy should be considered only if the potential benefit justifies the potential risk to the fetus. Mesalazine is excreted in breast milk; caution is advised when administered to nursing mothers.
Key Drug Interactions
- May interact with other drugs that affect renal function.
- Caution with concomitant use of non-steroidal anti-inflammatory drugs (NSAIDs).
Contraindications
- Hypersensitivity to mesalazine or any component of the formulation.
- Severe renal impairment.
- Active gastrointestinal bleeding.
Common side effects
- Abdominal pain
- Diarrhea
- Nausea
- Headache
- Rash
Counselling Points
- Advise patients to maintain adequate hydration.
- Instruct patients to report any signs of allergic reactions or severe gastrointestinal symptoms.
- Emphasize the importance of adherence to the prescribed regimen.
Serious warnings
- Monitor renal function regularly during treatment.
- Use with caution in patients with a history of asthma or hypersensitivity to sulfasalazine.
- Discontinue use if severe skin reactions occur.
Important Disclaimer
The Asacol 500mg Suppositories professional information leaflet below is the property of Equity Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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