Palonosetron 0,25 Teva 0,25 mg Solution for injection;
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of acute nausea and vomiting from chemotherapy.
Dosage (summary)
0.25 mg IV bolus 30 mins before chemotherapy.
Onset of Action / Duration
Onset: 30 mins, Duration: Not specified
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; discontinue breastfeeding during therapy.
Key Drug Interactions
- CYP2D6 inducers/inhibitors
- Serotonergic medications
- Corticosteroids
Contraindications
- Hypersensitivity to palonosetron or excipients
Common side effects
- Headache
- Constipation
Counselling Points
- Monitor for constipation
- Caution when driving or operating machinery
- Report any adverse reactions
Serious warnings
- Risk of serotonin syndrome
- Monitor for myocardial ischemia
- QT prolongation caution
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