Daprohin 400/50 Mg 400 mg, 40 mg Tablet
PDF Leaflet Revision Date: 25 July 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV infection in antiretroviral treatment experienced adult patients.
Dosage (summary)
800/100 mg once daily with food for adults.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; potential serious adverse events in nursing infants.
Key Drug Interactions
- CYP3A inhibitors
- Anticonvulsants
- Antihistamines
- Antidysrhythmics
- HMG-CoA reductase inhibitors
Contraindications
- Hypersensitivity to darunavir or ritonavir
- Severe hepatic impairment
- Co-administration with certain CYP3A substrates
Common side effects
- Rash
- Nausea
- Diarrhea
- Headache
- Fatigue
Counselling Points
- Take with food
- Monitor for skin reactions
- Avoid certain drug interactions
- Regular liver function tests recommended
Serious warnings
- Severe skin reactions
- Hepatotoxicity
- Increased bleeding in hemophilia patients
Important Disclaimer
The Daprohin 400/50 Mg 400 mg, 40 mg Tablet professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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