Dobisim 20, 50 & 300 20 mg, 50 mg & 300 mg Solution for injection
PDF Leaflet Revision Date: 17 October 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Local anaesthetic for infiltration and field block anaesthesia.
Dosage (summary)
0.5-1.0% solution; max 300 mg/24 hours.
Special Populations
- Elderly
- Children
- Patients with hepatic impairment
- Patients with renal impairment
Pregnancy & Breastfeeding
Avoid in early pregnancy; small amounts excreted in breast milk.
Key Drug Interactions
- Other local anaesthetics
- Beta-blockers
- CYP1A2 inhibitors
Contraindications
- Hypersensitivity to lidocaine
- Heart block
- Bradycardia
- Hypovolaemia
- Myasthenia gravis
Common side effects
- Hypotension
- Dizziness
- Nausea
- Allergic reactions
Counselling Points
- Avoid driving after anaesthesia
- Monitor for allergic reactions
- Report any unusual symptoms immediately
Serious warnings
- Risk of systemic toxicity if administered intravenously
- Caution in patients with cardiovascular issues
- Potential for chondrotoxicity with intra-articular use
Important Disclaimer
The Dobisim 20, 50 & 300 20 mg, 50 mg & 300 mg Solution for injection professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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