Isoniazid 300 Adco 300 mg Tablet
PDF Leaflet Revision Date: 10 June 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis and treatment of tuberculosis.
Dosage (summary)
Adults: Prophylaxis 5 mg/kg (max 300 mg), Treatment 5-15 mg/kg (max 900 mg).
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Use in pregnancy with caution; not recommended during breastfeeding.
Key Drug Interactions
- CYP450 inhibitors
- Benzodiazepines
- Rifampicin
- Alcohol
Contraindications
- Hypersensitivity to isoniazid
- Alcoholism
- Severe renal failure
- Uncontrolled seizures
Common side effects
- Hepatitis
- Peripheral neuritis
- Optic neuritis
- Gastrointestinal irritation
Counselling Points
- Take on an empty stomach
- Avoid alcohol
- Report signs of liver dysfunction
- Supplement with pyridoxine if at risk of neuropathy
Serious warnings
- Hepatotoxicity risk
- Severe skin reactions
- Monitor for hypersensitivity
Important Disclaimer
The Isoniazid 300 Adco 300 mg Tablet professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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