Kaletra Solution 80 mg / 20mg Oral Solution
PDF Leaflet Revision Date: 25 June 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV infection in combination with other antiretroviral medicines.
Dosage (summary)
Adults: 400/100 mg (5 mL) twice daily or 800/200 mg (10 mL) once daily with food. Children: 12/3 mg/kg for 7-15 kg, 10/2.5 mg/kg for 15-40 kg, max 400/100 mg for >40 kg, twice daily with food.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not established in pregnancy; avoid breastfeeding due to HIV transmission risk.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Colchicine
- Rifampicin
- St. John's Wort
Contraindications
- Hypersensitivity to lopinavir or ritonavir
- Co-administration with certain CYP3A substrates
Common side effects
- Diarrhoea
- Nausea
- Vomiting
- Hypertriglyceridaemia
- Hypercholesterolaemia
Counselling Points
- Take with food
- Monitor for glucose levels
- Avoid alcohol and propylene glycol in infants
Serious warnings
- Risk of pancreatitis
- Potential for drug interactions
- Cardiac toxicity in overdose
Important Disclaimer
The Kaletra Solution 80 mg / 20mg Oral Solution professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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