Lopimune 40 mg and 10 mg CAPSULE (ORAL PELLETS)

    Lopimune 40 mg and 10 mg CAPSULE (ORAL PELLETS)

    S4
    PDF Leaflet Revision Date: 13 October 2025


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of HIV-1 infection in combination with other antiretrovirals.

    Dosage (summary)

    Adults: 400/100 mg twice daily; Children: weight-based dosing.

    Special Populations

    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy; avoid breastfeeding.

    Key Drug Interactions

    • CYP3A4 substrates
    • Rifampicin
    • Colchicine
    • PDE5 inhibitors

    Contraindications

    • Severe hepatic insufficiency
    • Hypersensitivity to components

    Common side effects

    • Diarrhoea
    • Nausea
    • Vomiting
    • Dyslipidaemia

    Counselling Points

    • Take with food
    • Do not chew or crush pellets
    • Monitor for liver function abnormalities

    Serious warnings

    • Risk of pancreatitis
    • Increased bleeding in haemophilia
    • Immune reactivation syndrome
    Important Disclaimer

    The Lopimune 40 mg and 10 mg CAPSULE (ORAL PELLETS) professional information leaflet below is the property of Cipla Medpro and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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