Mannitol 20 % Fresenius 500 ml Solution for infusion (parenteral).
PDF Leaflet Revision Date: 26 May 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Promotes diuresis, reduces intracranial pressure, and lowers intraocular pressure.
Dosage (summary)
50-200 g over 24 hours; test dose of 200 mg/kg for oliguria.
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established.
Key Drug Interactions
- Increased clearance of lithium
- Potentiation with other diuretics
Contraindications
- Hypersensitivity to mannitol
- Severe renal disease
- Pulmonary congestion
- Intracranial bleeding
- Congestive heart failure
Common side effects
- Headache
- Dizziness
- Nausea
- Fluid imbalance
- Oliguria
Counselling Points
- Monitor fluid and electrolyte balance
- Infusion site reactions possible
- Do not mix with blood
Serious warnings
- Risk of CNS toxicity
- Risk of renal complications
- Risk of hypervolaemia
Important Disclaimer
The Mannitol 20 % Fresenius 500 ml Solution for infusion (parenteral). professional information leaflet below is the property of Fresenius Kabi Manufacturing Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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