Pericob 40 40 mg Powder for solution for injection.

    Pericob 40 40 mg Powder for solution for injection.

    S3
    PDF Leaflet Revision Date: 24 October 2022

    API: Parecoxib | Company: Ascendis Pharma

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Short-term management of post-operative pain.

    Dosage (summary)

    Initial 40 mg IV/IM, then 20-40 mg every 6-12 hours, max 80 mg/day.

    Onset of Action / Duration

    Onset: 7-14 mins, Duration: 7-24 hours.

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy and breastfeeding.

    Key Drug Interactions

    • Warfarin
    • Other NSAIDs
    • ACE inhibitors

    Contraindications

    • Hypersensitivity to parecoxib
    • Active peptic ulceration
    • Severe hepatic impairment
    • Severe renal impairment
    • Congestive heart failure
    • Children under 18

    Common side effects

    • Nausea
    • Dizziness
    • Hypertension
    • Hypotension

    Counselling Points

    • Monitor for skin reactions.
    • Avoid in pregnancy and breastfeeding.
    • Report any signs of hypersensitivity.

    Serious warnings

    • Cardiovascular events risk
    • Gastrointestinal complications
    • Serious skin reactions
    Important Disclaimer

    The Pericob 40 40 mg Powder for solution for injection. professional information leaflet below is the property of Ascendis Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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