Lendidip 10 mg & 20 mg FC tablet

    Lendidip 10 mg & 20 mg FC tablet

    S3
    PDF Leaflet Revision Date: 08 July 2025


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of mild to moderate hypertension.

    Dosage (summary)

    Starting dose: 10 mg orally once daily before meals; may increase to 20 mg based on response.

    Onset of Action / Duration

    Onset: 2 weeks, Duration: 24 hours

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy or breastfeeding.

    Key Drug Interactions

    • CYP3A4 inhibitors (e.g., ketoconazole, grapefruit juice)
    • Ciclosporin
    • Inducers of CYP3A4 (e.g., phenytoin, rifampicin)
    • Alcohol

    Contraindications

    • Hypersensitivity to lercanidipine
    • Left ventricular outflow tract obstruction
    • Untreated congestive cardiac failure
    • Unstable angina pectoris
    • Severe hepatic impairment
    • Severe renal impairment
    • Co-administration with strong CYP3A4 inhibitors

    Common side effects

    • Headache
    • Dizziness
    • Tachycardia
    • Flushing
    • Hypotension

    Counselling Points

    • Take at least 15 minutes before meals
    • Avoid alcohol
    • Monitor blood pressure regularly

    Serious warnings

    • Caution in patients with sick sinus syndrome
    • Increased cardiovascular risk in ischaemic heart disease
    Important Disclaimer

    The Lendidip 10 mg & 20 mg FC tablet professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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