Zytram Tablet
PDF Leaflet Revision Date: 8 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of moderate to severe pain.
Dosage (summary)
Initial dose: 150 mg daily; titrate as needed, max 400 mg/day.
Special Populations
- Elderly patients
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- MAO inhibitors
- CNS depressants
- SSRIs/SNRIs
Contraindications
- Hypersensitivity
- Acute intoxication with CNS depressants
- Postoperative pain management in children <18 years
Common side effects
- Nausea
- Dizziness
- Somnolence
- Constipation
Counselling Points
- Take whole, do not crush or chew
- Monitor for signs of dependence
- Avoid alcohol and CNS depressants
Serious warnings
- Risk of dependence and withdrawal symptoms
- Convulsions may occur
- Respiratory depression risk
Important Disclaimer
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